Melanotan II

★ 65

Melanotan II (MT-II)

Bronze tan + libido

Sexual Health

Half-life

~1 hour

Route

SubQ

Cycle

Loading 4-8 weeks,

Status

Not approved — research compound

About

A cyclic melanocortin receptor agonist — developed as a tanning peptide. Also has libido effects.

Mechanism

Activates MC1R (melanin, tanning) and MC3R/MC4R (libido, appetite).

Dosage

beginner

Amount: 250 mcg
Frequency: 1x per day (loading)
Route: SubQ
Duration: 4-8 weeks loading

standard

Amount: 500 mcg
Frequency: 1x per day (loading), then 2-3x/week maintenance
Route: SubQ
Duration: Loading 4-8 weeks, then maintenance

advanced

Amount: 1000 mcg
Frequency: 1x per day loading, then 2-3x/week
Route: SubQ
Duration: Continuous with breaks

Timing

In the evening (usually). UV exposure (sun/tanning bed) is needed for 1-2 days after dosing to activate the tan.

Cycle structure

Loading 4-8 weeks, then low-dose maintenance.

Reconstitution & Storage

10 mg + 3 mL → 3.33 mg/mL

10 units on an insulin syringe = 333 mcg.

Lyophilized: freezer. Reconstituted: 2-8°C, 4-6 weeks.

Benefits

• Dark and long-lasting tan
• Sunburn protection (theoretical)
• Increased libido
• Reduced appetite (bonus)

Side effects

• Nausea (common at first)
• Flushing
• Darkening of freckles and moles
• Spontaneous erections (men)
• IMPORTANT: monitor any new or changed moles

Contraindications

• History of melanoma
• Many moles on the skin
• Familial dysplastic nevus syndrome
• Pregnancy
• Cardiovascular disease

Gender notes

Men

Sometimes causes unexpected erections initially. Lower doses are often sufficient.

Women

Popular for tanning. Caution with moles — see a dermatologist regularly.

Research

Dorr RT et al: Melanotan II safety study ↗
Early clinical trial of MT-II in healthy volunteers.

Life Sciences · 1996
Hadley ME: Discovery of melanocortin sexual function ↗
Review of the discovery that melanocortins regulate sexual function.

Peptides · 2005

Stacks well with

PT-141

Track Melanotan II doses in the app

Built-in reconstitution calculator, dose log, and reminders. Free on Android.

Get on Google Play

Educational use only. Not medical advice. Many peptides shown are not FDA-approved and remain research compounds. Always consult a qualified healthcare provider.