DSIP

★ 70

Delta Sleep-Inducing Peptide

Deep sleep and delta waves

Sleep

Half-life

Short (~7 min) but biological effects are sustained

Route

SubQ

Cycle

Can be used

Status

Limited Western trials

About

A naturally occurring peptide that promotes delta-wave sleep. Induces deep, restorative sleep.

Mechanism

Promotes delta-wave activity on EEG. Modulates the circadian rhythm.

Dosage

beginner

Amount: 100 mcg
Frequency: 1x per day before sleep
Route: SubQ
Duration: As long as needed

standard

Amount: 100-200 mcg
Frequency: 1x per day before sleep
Route: SubQ
Duration: 4-8 week cycle

advanced

Amount: 200-500 mcg
Frequency: 1x per day before sleep
Route: SubQ
Duration: Cycled 4-6 weeks

Timing

30 min before sleep.

Cycle structure

Can be used daily long-term but also cycled 4-6 weeks on, 1-2 weeks off.

Reconstitution & Storage

5 mg + 2.5 mL → 2 mg/mL

Low dose, so 2.5 mL is convenient.

Lyophilized: freezer. Reconstituted: 2-8°C, 30 days.

Benefits

• Deep sleep (slow-wave sleep)
• Faster sleep onset
• Improved morning energy
• Stress reduction
• Possibly helpful for alcohol withdrawal
• No morning grogginess

Side effects

• Very well tolerated
• Rare: vivid dreams

Contraindications

• Pregnancy
• Other sleep medications (possible interaction)

Gender notes

Men

Same dose. Popular for shift workers.

Women

Same dose. Highly effective for menopause-related sleep problems.

Research

Schneider-Helmert D: DSIP for sleep disorders ↗
Clinical trial of DSIP for chronic insomnia.

European Neurology · 1987
Graf MV, Kastin AJ: DSIP biological actions ↗
Review of DSIP's biological actions.

Neuroscience & Biobehavioral Reviews · 1986

Stacks well with

EPITALON IPAMORELIN SELANK

Track DSIP doses in the app

Built-in reconstitution calculator, dose log, and reminders. Free on Android.

Get on Google Play

Educational use only. Not medical advice. Many peptides shown are not FDA-approved and remain research compounds. Always consult a qualified healthcare provider.