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Ipamorelin

★ 92

Ipamorelin

Clean GH pulse without cortisol elevation

Muscle Growth
Half-life
~2 hours
Route
SubQ
Cycle
12-16 weeks on,
Status
Phase II trials completed

About

A selective ghrelin receptor agonist that stimulates growth hormone release without raising cortisol or prolactin.

Mechanism

Binds GHS-R1a receptors in the pituitary and triggers a clean GH pulse.

Dosage

beginner

Amount
100 mcg
Frequency
1x per day before sleep
Route
SubQ
Duration
8-12 weeks

standard

Amount
200-300 mcg
Frequency
1-2x per day (evening + morning)
Route
SubQ
Duration
12-16 weeks

advanced

Amount
300 mcg
Frequency
3x per day (morning, pre-workout, evening)
Route
SubQ
Duration
12-16 weeks with breaks
Timing

On an empty stomach, 30-60 min before food or sleep. Important: no food for 30-60 min after.

Cycle structure

12-16 weeks on, 4 weeks off to avoid receptor desensitization

Reconstitution & Storage

10 mg + 2 mL → 5000 mcg/mL

Often blended with CJC-1295 in the same syringe.

Dosing reference — units to draw

Concentration = peptide mass ÷ bacteriostatic water; units to draw = dose volume (mL) × 100 on a U-100 insulin syringe. Each vial size below is shown at 2 mL, with the units to draw for a typical 200–300 mcg dose.

Ipamorelin reconstitution: vial size, bacteriostatic water, resulting concentration, and units to draw on a U-100 insulin syringe for a typical dose.
Vial BAC water Concentration Units to draw
10 mg 2 mL 5000 mcg/mL 4–6 units

Open Ipamorelin in the reconstitution calculator →

Lyophilized: freezer. Reconstituted: 2-8°C, 28 days.

Benefits

  • • Natural GH elevation
  • • Improved sleep
  • • Muscle building
  • • Fat loss
  • • Improved skin and hair quality
  • • No cortisol elevation

Side effects

  • • Tingling in hands (transient)
  • • Vivid dreams
  • • Transient headache
  • • Mild hunger

Contraindications

  • • Active cancer (hard contraindication)
  • • Pregnancy and breastfeeding
  • • Diabetes (monitor blood glucose)
  • • Pituitary tumors

Gender notes

Men

Common dose 200-300 mcg. Indirectly supports testosterone optimization.

Women

Start at 100-150 mcg. Hormone sensitivity is higher. Excellent for aging and skin health.

Research

Stacks well with

Ipamorelin FAQ

How do you reconstitute Ipamorelin?

Add 2 mL of bacteriostatic water to a 10 mg vial of Ipamorelin, which gives a concentration of 5000 mcg/mL. Inject the water slowly down the vial wall and swirl gently — never shake.

What is a typical Ipamorelin dose?

A typical research dose of Ipamorelin is 200–300 mcg, 1-2x per day (evening + morning). This is educational information, not medical advice.

How many units of Ipamorelin do I draw?

From a 10 mg vial reconstituted with 2 mL of bacteriostatic water, draw 4–6 units on a U-100 insulin syringe for a 200–300 mcg dose.

Track Ipamorelin doses in the app

Built-in reconstitution calculator, dose log, and reminders. Free on Android.

Get on Google Play

Educational use only. Not medical advice. Many peptides shown are not FDA-approved and remain research compounds. Always consult a qualified healthcare provider.