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GHRP-2

★ 70

Growth Hormone Releasing Peptide-2 (Pralmorelin)

Classic GH releaser — stronger pulse than Ipamorelin

Muscle Growth
Half-life
~15-60 minutes (SubQ)
Route
SubQ
Cycle
12-16 weeks on,
Status
Studied since the 1990s for GH deficiency

About

A synthetic ghrelin receptor agonist that triggers strong GH release. More potent GH pulse than Ipamorelin but with side effects: elevated cortisol, prolactin, and intense hunger.

Mechanism

Binds GHS-R1a receptors in the pituitary to trigger GH release; also stimulates ghrelin's appetite pathway.

Dosage

beginner

Amount
100 mcg
Frequency
1x per day before sleep
Route
Subcutaneous (SubQ)
Duration
8-12 weeks

standard

Amount
100-200 mcg
Frequency
2x per day (AM + PM, empty stomach)
Route
SubQ
Duration
12-16 weeks

advanced

Amount
200-300 mcg
Frequency
3x per day (AM, post-workout, PM)
Route
SubQ
Duration
12-16 weeks with breaks
Timing

Empty stomach, 30-60 min before food. Avoid sugar/carbs 30 min before to prevent GH blunting.

Cycle structure

12-16 weeks on, 4-6 weeks off to reset receptors and stop prolactin creep.

Reconstitution & Storage

5 mg + 2 mL → 2500 mcg/mL

Frequently stacked with CJC-1295 in the same syringe.

Dosing reference — units to draw

Concentration = peptide mass ÷ bacteriostatic water; units to draw = dose volume (mL) × 100 on a U-100 insulin syringe. Each vial size below is shown at 2 mL, with the units to draw for a typical 150–300 mcg dose.

GHRP-2 reconstitution: vial size, bacteriostatic water, resulting concentration, and units to draw on a U-100 insulin syringe for a typical dose.
Vial BAC water Concentration Units to draw
5 mg 2 mL 2500 mcg/mL 6–12 units
10 mg 2 mL 5000 mcg/mL 3–6 units

Open GHRP-2 in the reconstitution calculator →

Lyophilized: freezer. Reconstituted: 2-8°C, 28 days.

Benefits

  • • Strong GH and IGF-1 elevation
  • • Improved sleep depth
  • • Muscle building
  • • Cheaper than Ipamorelin
  • • Useful for breaking lean-muscle plateaus

Side effects

  • • Intense hunger surge (often within 30 min)
  • • Elevated cortisol (transient stress)
  • • Elevated prolactin (can affect libido long-term)
  • • Water retention
  • • Tingling in hands

Contraindications

  • • Active cancer (hard contraindication)
  • • Pregnancy and breastfeeding
  • • Diabetes (monitor blood glucose)
  • • Pituitary tumors
  • • Hyperprolactinemia history

Gender notes

Men

Common dose 200-300 mcg, 2-3x daily. Watch for gyno from prolactin if running long cycles.

Women

Start at 100 mcg. Higher hormone sensitivity — prolactin elevation more impactful.

Research

Stacks well with

CJC-1295 IPAMORELIN BPC-157

GHRP-2 FAQ

How do you reconstitute GHRP-2?

Add 2 mL of bacteriostatic water to a 5 mg vial of GHRP-2, which gives a concentration of 2500 mcg/mL. Inject the water slowly down the vial wall and swirl gently — never shake.

What is a typical GHRP-2 dose?

A typical research dose of GHRP-2 is 150–300 mcg, 2x per day (am + pm, empty stomach). This is educational information, not medical advice.

How many units of GHRP-2 do I draw?

From a 5 mg vial reconstituted with 2 mL of bacteriostatic water, draw 6–12 units on a U-100 insulin syringe for a 150–300 mcg dose.

Track GHRP-2 doses in the app

Built-in reconstitution calculator, dose log, and reminders. Free on Android.

Get on Google Play

Educational use only. Not medical advice. Many peptides shown are not FDA-approved and remain research compounds. Always consult a qualified healthcare provider.