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Tesamorelin

★ 75 FDA approved

Tesamorelin (Egrifta)

GHRH analog targeting visceral fat

Fat Loss
Half-life
~26-38 min, but effects sustained
Route
SubQ
Cycle
16-26 weeks on,
Status
FDA approved 2010 for HIV-associated lipodystrophy

About

FDA-approved GHRH analog, used in HIV lipodystrophy. Highly effective for visceral fat reduction.

Mechanism

GHRH analog with a longer half-life, stimulating the GH/IGF-1 axis.

Dosage

beginner

Amount
1 mg
Frequency
1x per day before sleep
Route
SubQ
Duration
12 weeks

standard

Amount
2 mg
Frequency
1x per day before sleep
Route
SubQ
Duration
16-26 weeks

advanced

Amount
2 mg + 1 mg AM
Frequency
Split into two doses
Route
SubQ
Duration
26 weeks
Timing

On an empty stomach before sleep (30-60 min prior).

Cycle structure

16-26 weeks on, 4-8 weeks off

Reconstitution & Storage

10 mg + 1 mL → 10 mg/mL

Fragile — always store refrigerated after reconstitution.

Dosing reference — units to draw

Concentration = peptide mass ÷ bacteriostatic water; units to draw = dose volume (mL) × 100 on a U-100 insulin syringe. Each vial size below is shown at 1 mL, with the units to draw for a typical 1–2 mg dose.

Tesamorelin reconstitution: vial size, bacteriostatic water, resulting concentration, and units to draw on a U-100 insulin syringe for a typical dose.
Vial BAC water Concentration Units to draw
10 mg 1 mL 10 mg/mL 10–20 units

Open Tesamorelin in the reconstitution calculator →

Lyophilized: refrigerated. Reconstituted: 2-8°C, 7 days.

Benefits

  • • Significant visceral fat reduction
  • • Improved lipid profile
  • • Increased IGF-1
  • • Muscle building
  • • Improved energy

Side effects

  • • Facial flushing
  • • Tingling
  • • Fluid retention
  • • Joint pain
  • • Rare: elevated blood glucose

Contraindications

  • • Pituitary disease
  • • Active cancer
  • • Pregnancy
  • • Diabetes (requires monitoring)

Gender notes

Men

Same dose. Best for middle-age belly fat.

Women

Same dose, 1-2 mg. Highly effective for post-menopausal belly fat.

Research

Stacks well with

IPAMORELIN BPC-157

Tesamorelin FAQ

How do you reconstitute Tesamorelin?

Add 1 mL of bacteriostatic water to a 10 mg vial of Tesamorelin, which gives a concentration of 10 mg/mL. Inject the water slowly down the vial wall and swirl gently — never shake.

What is a typical Tesamorelin dose?

A typical research dose of Tesamorelin is 1–2 mg, 1x per day before sleep. This is educational information, not medical advice.

How many units of Tesamorelin do I draw?

From a 10 mg vial reconstituted with 1 mL of bacteriostatic water, draw 10–20 units on a U-100 insulin syringe for a 1–2 mg dose.

Track Tesamorelin doses in the app

Built-in reconstitution calculator, dose log, and reminders. Free on Android.

Get on Google Play

Educational use only. Not medical advice. Many peptides shown are not FDA-approved and remain research compounds. Always consult a qualified healthcare provider.